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Designed for high-throughput biological research, RASTRUM Allegro automates the generation of 3D cell models using drop-on-demand bioprinting and fully synthetic, tunable extracellular matrices. The video demonstrates the system’s ability to produce consistent, reproducible 3D models compatible with standard plate formats and screening workflows. Key applications include cancer research, immuno-oncology, and phenotypic drug discovery. The video provides a visual overview of the instrument’s performance, ease of use, and scalability, positioning RASTRUM Allegro as a next-generation platform for biologically relevant 3D cell modeling.https://inventialifescience.com/hubfs/Videos/RASTRUM%20Allegro%20Video%20Full%20Length.mp4109nonoRASTRUM Allegro3D BiologyRASTRUMhttps://inventialifescience.com/hubfs/RASTRUM_Allegro_User.webpScientist operating the RASTRUM Allegro 3D cell culture platform in a lab. 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The GIF highlights rapid, automated well-plate generation, demonstrating the platform’s ability to produce over 35 plates per day with precise, reproducible cell model formation.Image 2https://inventialifescience.com/hubfs/thumb-cell.jpgthumb-cellthumb-cellhttps://inventialifescience.com/hubfs/RASTRUM_Allegro_NHLF_HUVEC_A459_Phalloidin_ConA.webpFluorescent microscopy image of a 3D cell model grown using RASTRUM™ technology, showcasing complex tissue architecture and cellular interactions. 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This guide discusses key considerations for using 3D cell models in drug discovery research.tumor microenvironment product guidehttps://inventialifescience.com/hubfs/Cancer-Feature1-2.webpCancer-Feature1-2Cancer-Feature1-2https://inventialifescience.com/hubfs/beyond%20simple%20co-cultures.pngbeyond simple co-culturesbeyond simple co-cultureshttps://inventialifescience.com/hubfs/RASTRUM_Matrices_hero.webpRASTRUM_Matrices_heroRASTRUM_Matrices_herohttps://inventialifescience.com/hubfs/RASTRUM_Ovarian_A2780_Stiffness.webpRASTRUM_Ovarian_A2780_StiffnessRASTRUM_Ovarian_A2780_Stiffnesshttps://inventialifescience.com/hubfs/WebAssets-Hero/Hero%20Cloud.jpgHero CloudHero Cloudhttps://inventialifescience.com/hubfs/RASTRUM_TumorSpheroids_Recovery-1.webpRASTRUM_TumorSpheroids_Recovery-1RASTRUM_TumorSpheroids_Recovery-1https://inventialifescience.com/hubfs/RASTRUM_InertBase.webpRASTRUM_InertBaseRASTRUM_InertBasehttps://inventialifescience.com/hubfs/printable%20and%20tunable%20matrices.webpThumbnail of an application note titled "Printable and Tunable 3D Cell Culture Environments Using RASTRUM Matrices," showing a cover image of a scientist using lab equipment. 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Powered by the company’s proprietary RASTRUM™ bioprinting technology, LIGŌ is a handheld medical device that delivers advanced hydrogel materials directly into the body—allowing surgeons to reconstruct tissue architecture with greater control, speed, and precision. This video introduces the concept, development, and clinical potential of LIGŌ as a transformative tool for regenerative medicine. Designed for operating room use, LIGŌ enables spatially controlled delivery of bioinks to support wound healing and soft tissue regeneration in cases such as trauma, burns, and post-operative reconstruction. LIGO eliminates the need to print in vitro and then transplant. Instead, it brings the biofabrication process directly to the patient—bridging the gap between lab-based engineering and real-world clinical care. The system supports sterile, reproducible workflows and is engineered to meet the practical needs of clinicians and surgical teams. Backed by two successive grants from the NSW Health Medical Devices Fund, LIGŌ is moving toward clinical trials with strong support from Inventia’s research and clinical collaborators, including Concord Repatriation General Hospital. 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Designed for high-throughput biological research, RASTRUM Allegro automates the generation of 3D cell models using drop-on-demand bioprinting and fully synthetic, tunable extracellular matrices. The video demonstrates the system’s ability to produce consistent, reproducible 3D models compatible with standard plate formats and screening workflows. Key applications include cancer research, immuno-oncology, and phenotypic drug discovery. The video provides a visual overview of the instrument’s performance, ease of use, and scalability, positioning RASTRUM Allegro as a next-generation platform for biologically relevant 3D cell modeling.https://inventialifescience.com/hubfs/Videos/RASTRUM%20Allegro%20Video%20Full%20Length.mp4109nonoRASTRUM Allegro3D BiologyRASTRUMhttps://inventialifescience.com/hubfs/RASTRUM_Allegro_NHLF_HUVEC_A459_Phalloidin_ConA.webpFluorescent microscopy image of a 3D cell model grown using RASTRUM™ technology, showcasing complex tissue architecture and cellular interactions. The image highlights the tunable microenvironments designed for specific cell types and applications in drug discovery and disease research.RASTRUM_Allegro_NHLF_HUVEC_A459_Phalloidin_ConAhttps://inventialifescience.com/hubfs/Screenshot%202024-04-30%20at%204.38.24%20PM.pngA diagram showing how RASTRUM matrices can be tuned to replicate the stiffness of the tissues being modeled.Screenshot 2024-04-30 at 4.38.24 PMhttps://inventialifescience.com/hubfs/WebAssets-Content_Tile_Images/cells%20multigel.jpgTumor-fibroblast cell interactions within RASTRUM’s Triple Matrix Model architecturecells multigelhttps://inventialifescience.com/hubfs/A549_NHLF_DualMatrix_.webpRASTRUM 3D cell model of the tumor microenvironment with spatial separation in RASTRUM’s Dual Matrix Model architectureA549_NHLF_DualMatrix_https://inventialifescience.com/hubfs/image%20(30).pngimage (30)image (30)https://inventialifescience.com/hubfs/2d-3d-thumbnail-pink.png2d-3d-thumbnail-pink2d-3d-thumbnail-pinkhttps://inventialifescience.com/hubfs/descarga.webpdescargadescargahttps://inventialifescience.com/hubfs/RASTRUM_Cloud_Matrix_Discovery.webpStep-by-step selection process for RASTRUM Cloud Matrix Discovery, guiding users through matrix stiffness, adhesion peptides, and additive selection to create a customized 3D cell culture environment.RASTRUM_Cloud_Matrix_Discoveryhttps://inventialifescience.com/hubfs/RASTRUM%20Allegro%20Bench%20Closed.webpRASTRUM™ Allegro on a laboratory bench with its front panel closed, highlighting its compact design for scalable, reproducible 3D cell culture in drug discovery and disease research.RASTRUM Allegro Bench Closedhttps://inventialifescience.com/hubfs/Cell_Architectures_hero_image.pngCell_Architectures_hero_imageCell_Architectures_hero_imagehttps://inventialifescience.com/hubfs/Rastrum.webpRastrumRastrumhttps://inventialifescience.com/hubfs/Workflow%20Paths.jpegWorkflow PathsWorkflow Pathshttps://inventialifescience.com/hubfs/Fibroblast%20Figure%202%20copy.pngFibroblast Figure 2 copyFibroblast Figure 2 copyhttps://inventialifescience.com/hubfs/Discovery%20Services%20Hero%202026.jpgDiscovery Services Hero 2026Discovery Services Hero 2026https://inventialifescience.com/hubfs/allegro-bench-open-1200w.webpallegro-bench-open-1200wallegro-bench-open-1200whttps://inventialifescience.com/hubfs/RASTRUM_Cloud_walkthrough.gifRASTRUM_Cloud_walkthroughRASTRUM_Cloud_walkthroughhttps://inventialifescience.com/hubfs/Validated-Solutions.webpGloved hands holding a 96-well microplate at the RASTRUM Allegro bioprinter, representing validated 3D cell culture workflowsValidated-Solutionshttps://inventialifescience.com/hubfs/Large_Plug_Model_Data_Architecture.pngLarge_Plug_Model_Data_ArchitectureLarge_Plug_Model_Data_Architecturehttps://inventialifescience.com/hubfs/patient%20specific%20tumoroid.pngpatient specific tumoroidpatient specific tumoroidhttps://inventialifescience.com/hubfs/PBMCs_A549_Mematix-1.webpPBMCs_A549_Mematix-1PBMCs_A549_Mematix-1https://inventialifescience.com/hubfs/2d-3d-guide%20transparent%20v2.webpCover image of the 'Phenotypic 3D Cell Models: Benefits and How to Get Started' guide. Learn how 3D models improve drug discovery by offering more relevant and reproducible insights compared to traditional 2D cultures.2d-3d-guide transparent v2https://inventialifescience.com/hubfs/RASTRUM%20Allegro%20Bench%20Open_highres%20(1).webpRASTRUM™ Allegro on a laboratory bench with its front panel open, showcasing its high-throughput 3D cell culture capabilities. Designed for scalable, reproducible research in drug discovery, cancer biology, and regenerative medicine.RASTRUM Allegro Bench Open_highres (1)https://inventialifescience.com/hubfs/RASTRUM_Allegro_cell%20efficiency.pngRASTRUM_Allegro_cell efficiencyRASTRUM_Allegro_cell efficiencyhttps://inventialifescience.com/hubfs/Discovery-Mode.webpDiscovery-ModeDiscovery-Modehttps://inventialifescience.com/hubfs/RASTRUM_Drug_Discovery_Hero.webpRASTRUM 3D cell models and drug discoveryRASTRUM_Drug_Discovery_Hero2026-08-23 https://inventialifescience.com/resources/publications/egfr-and-pi3k-signalling-pathways-as-promising-targets-on-ctcs-from-patients-with-metastatic-gastric-adenocarcinomahttps://inventialifescience.com/hubfs/Publications_Website_Preview%20(4).pngPublications_Website_Preview (4)Publications_Website_Preview (4)2025-05-19 https://inventialifescience.com/resources/publications/anticancer-effect-of-ptiiphensshttps://inventialifescience.com/hubfs/publication-banner%20-%20anticancer.pngpublication-banner - anticancerpublication-banner - anticancer2026-07-23 https://inventialifescience.com/resources/application-note/tunable-matriceshttps://inventialifescience.com/hubfs/Imported_Blog_Media/6d52d20d-3dde-4c21-a297-e4c8f2aa53ed_Tunable%20Matrix_AppNote_Transparent.png6d52d20d-3dde-4c21-a297-e4c8f2aa53ed_Tunable Matrix_AppNote_Transparent6d52d20d-3dde-4c21-a297-e4c8f2aa53ed_Tunable Matrix_AppNote_Transparent2024-10-28 https://inventialifescience.com/resources/protocols/in-situ-celltiter-glo-3d-assay-for-rastrum-3d-advanced-modelshttps://inventialifescience.com/hubfs/CTG_Protocol_Transparent.webpCTG_Protocol_TransparentCTG_Protocol_Transparenthttps://inventialifescience.com/hubfs/CTG_GraphicalProtocol_Website.webpCTG_GraphicalProtocol_WebsiteCTG_GraphicalProtocol_Website2024-11-25 https://inventialifescience.com/resources/webinars/new-advancements-for-generating-more-accurate-2d-and-3d-modelshttps://inventialifescience.com/hubfs/SelectScience%20Bitbio%20Inventia%20Webinar.pngSelectScience Bitbio Inventia WebinarSelectScience Bitbio Inventia Webinar2024-12-02 https://inventialifescience.com/platform/workflow-paths/validated-solutions/fibroblast-activationhttps://inventialifescience.com/hubfs/ROI_fibro2_c2-2.webpROI_fibro2_c2-2ROI_fibro2_c2-2https://inventialifescience.com/hubfs/Validated%20Solutions.jpegValidated SolutionsValidated Solutionshttps://inventialifescience.com/hubfs/Asset%202@4x.webpAsset 2@4xAsset 2@4xhttps://inventialifescience.com/hubfs/Discovery%20Mode.jpegDiscovery ModeDiscovery Modehttps://inventialifescience.com/hubfs/Fig3C.webpFig3CFig3Chttps://inventialifescience.com/hubfs/hero-discovery-1200w.webphero-discovery-1200whero-discovery-1200whttps://inventialifescience.com/hubfs/fibroblast%20fig1.webpfibroblast fig1fibroblast fig12026-07-28 https://inventialifescience.com/platform/workflow-paths/discovery-modehttps://inventialifescience.com/hubfs/RASTRUM_Cloud_Matrix_Discovery.webpStep-by-step selection process for RASTRUM Cloud Matrix Discovery, guiding users through matrix stiffness, adhesion peptides, and additive selection to create a customized 3D cell culture environment.RASTRUM_Cloud_Matrix_Discoveryhttps://inventialifescience.com/hubfs/thumb-cell.jpgthumb-cellthumb-cellhttps://inventialifescience.com/hubfs/RASTRUM_Allegro_User.webpScientist operating the RASTRUM Allegro 3D cell culture platform in a lab. The system enables high-throughput, reproducible 3D cell model generation for drug discovery and translational research.RASTRUM_Allegro_Userhttps://inventialifescience.com/hubfs/Workflow%20Paths.jpgWorkflow PathsWorkflow Pathshttps://inventialifescience.com/hubfs/RASTRUM%20Allegro%20Workflow.webpStep-by-step process for generating 3D cell models with RASTRUM Allegro: select matrix, choose architecture, prepare cells, print models, and perform downstream analysis for high-throughput drug discovery and biomedical research.RASTRUM Allegro Workflowhttps://inventialifescience.com/hubfs/Validated%20Solutions.jpegValidated SolutionsValidated Solutionshttps://inventialifescience.com/hubfs/Cell_Architectures_hero_image.pngCell_Architectures_hero_imageCell_Architectures_hero_imagehttps://inventialifescience.com/hubfs/Inventia_Rastrum_Images/Small%20Tile%20Matrices.jpgSmall Tile MatricesSmall Tile Matriceshttps://inventialifescience.com/hubfs/Discovery%20Mode.jpgDiscovery ModeDiscovery Mode2026-07-28 https://inventialifescience.com/resources/protocols/handling-of-rastrum-removable-models/https://inventialifescience.com/hubfs/%2BGraphic.webp+Graphic+Graphic2024-11-25 https://inventialifescience.com/resources/posters/video-poster-presentation-bioprinted-multicellular-microenvironments-to-accelerate-immunotherapy-discovery-in-pancreatic-cancerhttps://inventialifescience.com/hubfs/Videos/AACR%202026%20-%20Bioprinted%20multicellular%20microenvironments%20to%20accelerate%20immunotherapy.mp4/medium.jpgScientific Poster - Bioprinted multicellular microenvironmentsAACR 2026 - Bioprinted multicellular microenvironments to accelerate immunotherapyhttps://inventialifescience.com/hubfs/Videos/AACR%202026%20-%20Bioprinted%20multicellular%20microenvironments%20to%20accelerate%20immunotherapy.mp4402nonohttps://inventialifescience.com/hubfs/AACR%202026%20Poster%20Video%20Immunotherapy%20thumbnail.pngAACR 2026 Poster Video Immunotherapy thumbnailAACR 2026 Poster Video Immunotherapy thumbnail2026-08-13 https://inventialifescience.com/resources/press-release/inventia-life-science-announces-35-million-dollar-series-b-fundinghttps://inventialifescience.com/hubfs/Inventia.webpInventiaInventia2024-03-06 https://inventialifescience.com/resources/newsroom/australian-3-d-cell-printing-company-completes-latest-funding-roundhttps://inventialifescience.com/hubfs/Inventia_January2024/images/cd1a9ad3-0fc9-4a3a-840c-3d1437669124_WSJ%2Barticle%2Bpreview.pngcd1a9ad3-0fc9-4a3a-840c-3d1437669124_WSJ+article+previewcd1a9ad3-0fc9-4a3a-840c-3d1437669124_WSJ+article+preview2024-02-15 https://inventialifescience.com/platform/rastrum-cloudhttps://inventialifescience.com/hubfs/RASTRUM%20Cloud%20v.05.mp4/medium.jpgRASTRUM CloudSee how RASTRUM Cloud helps researchers plan, adapt, and collaborate on reproducible 3D cell culture experiments through an intuitive, web-based interface.https://inventialifescience.com/hubfs/RASTRUM%20Cloud%20v.05.mp4245nonolabsoftware,biotechsoftware,rastrum,rastrumallegro,rastrumsoftware,3dbiology,3dbiologysoftware,cellbiology,cellbiologysoftwarehttps://inventialifescience.com/hubfs/WebAssets-Hero/Hero%20Cloud.jpgHero CloudHero Cloudhttps://inventialifescience.com/hubfs/RASTRUM_Cloud_Optimization_Adjusted.webpAchieve the ideal cell density for your 3D cell model experiments with step-by-step guidance from RASTRUM CloudRASTRUM_Cloud_Optimization_Adjustedhttps://inventialifescience.com/hubfs/Inventia_Rastrum_Images/Small%20Tile%20Matrices.jpgSmall Tile MatricesSmall Tile Matriceshttps://inventialifescience.com/hubfs/RASTRUM_Allegro_User.webpScientist operating the RASTRUM Allegro 3D cell culture platform in a lab. The system enables high-throughput, reproducible 3D cell model generation for drug discovery and translational research.RASTRUM_Allegro_Userhttps://inventialifescience.com/hubfs/RASTRUM_Cloud_Quote.webpRASTRUM Cloud Quote interface displaying a generated product quotation for a PrintRun, including catalog ID, product description, pricing details, and download options for finalizing the order.RASTRUM_Cloud_Quotehttps://inventialifescience.com/hubfs/RASTRUM_Cloud_Matrix_Discovery.webpStep-by-step selection process for RASTRUM Cloud Matrix Discovery, guiding users through matrix stiffness, adhesion peptides, and additive selection to create a customized 3D cell culture environment.RASTRUM_Cloud_Matrix_Discoveryhttps://inventialifescience.com/hubfs/RASTRUM_Cloud_Hero.gifRASTRUM Cloud is intuitive, user-friendly software designed to guide you through every step of 3D cell model creationRASTRUM_Cloud_Herohttps://inventialifescience.com/hubfs/RASTRUM_Cloud_PrintRun_Design%20(1).webpRASTRUM Cloud Print Run Design process visualizing the assignment of cell models to well plates, configuration of matrix conditions, and generation of a PrintRun protocol for downstream analysis.RASTRUM_Cloud_PrintRun_Design (1)2026-07-28 https://inventialifescience.com/resources/posters/preclinical-study-of-a-combinational-approach-for-ovarian-cancer-modelshttps://inventialifescience.com/hubfs/Poster%20Banner%20-%20Ovarian.pngPoster Banner - OvarianPoster Banner - Ovarian2025-09-22 https://inventialifescience.com/resources/publications/repurposing-of-ivacaftor-shows-potential-to-treat-ror1-expressing-high-grade-serous-ovarian-cancerhttps://inventialifescience.com/hubfs/marsh-trial-repurposing-publication.pngmarsh-trial-repurposing-publicationmarsh-trial-repurposing-publication2026-01-15 https://inventialifescience.com/resources/blog/breaking-resistance-how-3d-cell-models-are-changing-the-fight-against-ovarian-cancerhttps://inventialifescience.com/hubfs/Esther%20Rodman%20Blog%20Post%20Banner.pngEsther Rodman Blog Post BannerEsther Rodman Blog Post Banner2025-04-14 https://inventialifescience.com/resources/application-note/scalability-and-reproducibility-for-high-throughput-biological-modeling-in-3d-cell-culturehttps://inventialifescience.com/hubfs/App%20Note%20Banner%20-%20Horizontal%20-%20Scalability%20and%20reproducibility%20for%20high-throughput%20biological%20modeling%20in%203D%20cell%20culture-1.pngApp Note Banner - Horizontal - Scalability and reproducibility for high-throughput biological modeling in 3D cell culture-1App Note Banner - Horizontal - Scalability and reproducibility for high-throughput biological modeling in 3D cell culture-12025-01-28 https://inventialifescience.com/resources/blog/what-aacr-2026-revealed-about-the-future-of-cancer-researchhttps://inventialifescience.com/hubfs/Blog%20Post%20Banner%20-%20AACR%202026%20Insights.pngBlog Post Banner - AACR 2026 InsightsBlog Post Banner - AACR 2026 Insights2026-05-19 https://inventialifescience.com/resources/webinars/harnessing-advanced-cell-culture-models-for-drug-discovery-breakthroughs2025-08-19 https://inventialifescience.com/resources/webinars/cancer-cells-on-the-movehttps://inventialifescience.com/hubfs/DemandWebinar_WebsitePreview.webpDemandWebinar_WebsitePreviewDemandWebinar_WebsitePreview2024-10-28 https://inventialifescience.com/resources/protocols/qpcr-gene-expression-analysis-from-rastrum-advanced-cell-modelshttps://inventialifescience.com/hubfs/Imported_Blog_Media/e40b180e-8f7d-4585-8bce-fdadec3fc480_qPCR%20Gene%20Expression_Protocol_Transparent.pnge40b180e-8f7d-4585-8bce-fdadec3fc480_qPCR Gene Expression_Protocol_Transparente40b180e-8f7d-4585-8bce-fdadec3fc480_qPCR Gene Expression_Protocol_Transparenthttps://inventialifescience.com/hubfs/Protocol_qPCR.webpProtocol_qPCRProtocol_qPCR2024-11-25 https://inventialifescience.com/resources/publications/epigenetic-compound-library-screen-identifies-ibrutinib-as-an-inhibitor-of-ovarian-clear-cell-carcinoma-viabilityhttps://inventialifescience.com/hubfs/ibrutinib%20repurposing%20publication.pngibrutinib repurposing publicationibrutinib repurposing publication2026-04-30 https://inventialifescience.com/resources/publications/chemotherapeutic-potential-of-chlorambucil-platinumiv-prodrugshttps://inventialifescience.com/hubfs/chemotherapeutic-potential-render.pngchemotherapeutic-potential-renderchemotherapeutic-potential-render2025-05-19 https://inventialifescience.com/resources/newsroom/podcasts/julio-ribeiro-elevating-the-voices-of-leaders-in-life-science-stem-across-the-globe/https://inventialifescience.com/hubfs/Julio.webpJulioJulio2024-02-15 https://inventialifescience.com/applications-services/cancerhttps://inventialifescience.com/hubfs/RASTRUM_Allegro_NHLF_HUVEC_A459_Phalloidin_ConA.webpFluorescent microscopy image of a 3D cell model grown using RASTRUM™ technology, showcasing complex tissue architecture and cellular interactions. The image highlights the tunable microenvironments designed for specific cell types and applications in drug discovery and disease research.RASTRUM_Allegro_NHLF_HUVEC_A459_Phalloidin_ConAhttps://inventialifescience.com/hubfs/Validated-Solutions.webpGloved hands holding a 96-well microplate at the RASTRUM Allegro bioprinter, representing validated 3D cell culture workflowsValidated-Solutionshttps://inventialifescience.com/hubfs/2D_3D_Cell_Model_Comparison.webpRASTRUM enables scalable, reproducible, and biologically relevant 3D cell models compared to 2D cell culture or suspension cultures.2D_3D_Cell_Model_Comparisonhttps://inventialifescience.com/hubfs/RASTRUM_Precision_Medicine_Culture.webpThe figure depicts bright-field images of patient-derived colorectal cancer cells grown as tumoroids in suspension cultures at day 6 (left) or in Px02 RASTRUM matrices at day 7 (right).RASTRUM_Precision_Medicine_Culturehttps://inventialifescience.com/hubfs/Orthogonal%20Projection%20(1).pngOrthogonal Projection (1)Orthogonal Projection (1)https://inventialifescience.com/hubfs/WebAssets-Diagrams/Matrices%20diagram%20Cnr%20radius%2030.pngMatrices diagram Cnr radius 30Matrices diagram Cnr radius 30https://inventialifescience.com/hubfs/thumb-cell.jpgthumb-cellthumb-cellhttps://inventialifescience.com/hubfs/PANC_TCell_BME_RASTRUM.webpA comparison of activated cytotoxic T lymphocytes (CTLs) infiltration of pancreatic cancer cells cultured in 4.8kPa RASTRUM matrices compared to basement membrane extract (BME).PANC_TCell_BME_RASTRUMhttps://inventialifescience.com/hubfs/WebAssets-Content_Tile_Images/cells%20multigel.jpgTumor-fibroblast cell interactions within RASTRUM’s Triple Matrix Model architecturecells multigelhttps://inventialifescience.com/hubfs/A549_NHLF_DualMatrix_.webpRASTRUM 3D cell model of the tumor microenvironment with spatial separation in RASTRUM’s Dual Matrix Model architectureA549_NHLF_DualMatrix_https://inventialifescience.com/hubfs/Cancer-Feature1.webpCancer-Feature1Cancer-Feature1https://inventialifescience.com/hubfs/RASTRUM_Allegro_User.webpScientist operating the RASTRUM Allegro 3D cell culture platform in a lab. 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Features a preview of the document, with fluorescent neuron images and a "Download Now" button. 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