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RASTRUM Allegro bioprinter generating reproducible 3D cell models in a 384-well plate

Discovery Mode

 

Flexible 3D model development with RASTRUM

Define and refine 3D cell models on RASTRUM using Inventia Life Science best practices, then tailor parameters to match your biology and readouts. 
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When to Use Discovery Mode

Choose Discovery Mode when you need a model built to your specifications or when no Validated Solution exists for your biology, cells, or constraints.

Use Discovery Mode when you want to:

• Define success criteria, phenotype, functional readouts, and acceptance thresholds


• Fit the model to your cell sources, media, experimental timelines, and downstream assay stack


• Explore multiple architectures and conditions to unlock  the biology you need


• Build a workflow that matches your program requirements 


• Establish a baseline you can standardize and scale later
Step-by-step process for generating 3D cell models with RASTRUM Allegro: select matrix, choose architecture, prepare cells, print models, and perform downstream analysis for high-throughput drug discovery and biomedical research.

Choose Discovery Mode when you need a flexible starting point, guided by Inventia recommendations, to build a model that matches your biology and program requirements.
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Step-by-step selection process for RASTRUM Cloud Matrix Discovery, guiding users through matrix stiffness, adhesion peptides, and additive selection to create a customized 3D cell culture environment.

How Discovery Mode Works

  1. Define your biological objective

    Identify the biology, phenotype, and readouts you need.

  2. Configure your model in RASTRUM Cloud

    Select matrix chemistry, cell model architecture, cell densities, and culture parameters.

  3. Build and refine your 3D model

    Iterate experimental conditions until the biology is established.

  4. Apply QC checkpoints

    Confirm model reproducibility and experimental consistency.

  5. Execute downstream assays

    Integrate imaging, functional assays, perturbation experiments, or multi-omics analysis.
Validated Solutions

Prefer a proven starting point?

Validated Solutions provide defined build parameters plus functional validation and benchmarks, tied to a specific context of use.
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FAQs
What is Discovery Mode?
Discovery Mode is a flexible RASTRUM workflow path for researchers who need to design, build, and optimize a new 3D cell model. It is used when an existing Validated Solution does not match the biology, cell type, assay, or experimental constraints of the project.
When should researchers use Discovery Mode?
Researchers should use Discovery Mode when they need flexibility to create or adapt a 3D model around a specific cell type, disease biology, matrix, model architecture, assay, or readout. It is best suited for exploratory workflows where the optimal model parameters still need to be defined.
What is the difference between Discovery Mode, Validated Solutions, and Discovery Services?
Discovery Mode supports flexible development of new or customized 3D models. Validated Solutions provide predefined workflows for specific contexts of use. Discovery Services provides Inventia scientific support to develop, run, optimize, or transfer 3D disease model workflows when additional customization or study execution is needed.