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Fibroblast Activation Validated Solution Data Pack

Written by Inventia | Apr 16 2026

Overview

The Fibroblast Activation Validated Solution is part of the RASTRUM Validated Solution offering and provides a standardized workflow for generating normal human lung fibroblast (NHLF) 3D cell models using the RASTRUM platform. The workflow supports TGF-β induction of fibroblast activation and validation of activated phenotypes via immunofluorescent staining and gene expression analysis under defined operating conditions. This Data Pack contains example data for this reproducible 3D fibroblast model designed for translational research workflows.

What’s included

  • Morphology of NHLF in RASTRUM Matrix versus basement membrane extract
  • Growth and viability data for NHLF in RASTRUM models
  • Collagen I expression data in NHLF in response to TGF-β stimulation
  • Comparison of immunofluorescence imaging in RASTRUM Matrix and BME